Ivan HOVANJEC1, Michal BERNADIČ2, Lucia ŽIDEKOVÁ3, Beata MLADOSIEVIČOVÁ1

1Ústav patologickej fyziológie, LF UK,  Bratislava, prednosta prof. MUDr. F. Šimko, PhD., FESC
2Klinika chirurgickej onkológie LF SZU a NOÚ, Bratislava, prednosta doc. MUDr. D. Pinďák, PhD.
3Medirex a.s., Bratislava

SUMMARY
Cardiovascular disease and cancer are leading causes of morbidity and mortality worldwide. Attention to shared risk factors between these diseases has been paid only in the last decade. Moreover, it was demonstrated that patients with heart failure  could be more susceptible to developing cancer as well as cancer patients have higher risk of cardiovascular diseases due to cardiotoxic treatment.  Additionally, cancer itself may have negative impact on cardiovascular health. This article summarizes several common risk factors and pathophysiological mechanisms  for both diseases. It also describes potential  effect of heart failure on  cancer.
Key words: cardiovascular disease, heart failure, cancer, shared risk factors.

Lek obz (Med Horizon), 2020, 69(1): 11-16