Anna GVOZDJÁKOVÁ, Jarmila KUCHARSKÁ, Zuzana RAUSOVÁ, Zuzana SUMBALOVÁ

Lekárska fakulta UK v Bratislave, Farmakobiochemické laboratórium III. internej kliniky LF UK a UNB Bratislava, vedúci pracoviska doc. MUDr. V. Mojto, CSc., MHA, MPH

SUMMARY
Alzheimer‘s disease (AD) is the most common form of dementia that affects 46 million people in the world. AD is associated with accumulation of Aβ-proteins in neurons, mitochondrial bioenergy dysfunction and oxidative stress. A new, non-invasive methodology of mitochondrial bioenergy in isolated platelets reveals changes early in AD. The aim of antioxidant and bioenergy therapy is to achieve „mitochondria health“.
Key words: Alzheimer´s disease, mitochondria, oxidative stress, antioxidants.

Lek Obz (Med Horizon), 2020, 69 (2): 51 – 54