Ivana BAČOVÁ1, Stanislava BACHLEDOVÁ2, Martina GÁBOROVÁ1, Pavol ŠVORC1, Viliam DONIČ1

1Ústav lekárskej fyziológie UPJŠ, Lekárska fakulta, Košice, prednosta prof. MUDr. V. Donič, CSc.
2Ambulancia praktického lekára pre dospelých – Garmedic, s.r.o., Košice, MUDr. S. Bachledová

SUMMARY
Background: Vitamin D is well- known for anti-carcinogenic, anti-inflammatory and anti-apoptotic effects. Vitamin D deficiency in an important risk factor for many different diseases. Goal of this study was to observe the prevalence of vitamin D deficiency in adult population.
Patients and methods: 150 patients (110 women, 40 men) of outpatient department was enrolled into this observational study, ranged in age 20 – 80 years. Vitamin D deficiency was stated by electrochemiluminescence laboratory method from October to March in years 2017– 2018. The control laboratory examination was realised in patients with deficiency after 2 months of supplementation.
Results: Hypovitaminosis was registered in 67 % of all patients (women 50 %, men 17 %). In age group 50 – 80 years of age there was 87 % prevalence of hypovitaminosis in women. In men of age group 50 – 80 years the prevalence was 80.1 %. Vitamin D values decreased obviously by aging in both groups. We could also observe significant increase of serum vitamin D concentrations (p < 0.0001) after 2 months of treatment.
Conclusion: Vitamin D deficiency is widespread in our adult population of all age categories. We registered significant increase of serum vitamin D concentrations after 2 months of supplementation but almost 60 % of patients have not reached the optimal levels with our treatment. Therefore, we think it is necessary to supplement vitamin D in larger concentrations that we have already done.
Key words: vitamin D, diagnosis of vitamin D deficiency, vitamin D supplementation.

Lek obz (Med Horizon), 2020, 69 (1): 2 – 6