Outbreak of KPC Klebsiella pneumoniae during second wave of COVID-19 pandemic in University hospital Trnava
SUMMARY
Introduction: The COVID-19 pandemic has brought an outbreak of multidrug-resistant strains in healthcare facilities. The study aimed to evaluate the epidemic investigation of KPC Klebsiella penumoniae at the University Hospital Trnava.
Methods: Outbreak report study of KPC Klebsiella pneumoniae cases in the period from March 2020 to March 2021. We used active surveillance of nosocomial infections according to ECDC definitions and antimicrobial resistance based on EUCAST recommendations. Epidemic measures provided by the Department of Hospital Hygiene and Epidemiology were applied. Statistical calculations were performed in the program R project and due to the significance, the value p 0.05 was determined.
Results: During the study period, we recorded a total of 80 cases of Klebsiella pneumoniae producing carbapenemases in 13 departments. There were 67.5% (54) of nosocomial infection, frequently in COVID-19 patients (p = 0.014). Respiratory infections were the most frequent type of infection (39; 72.2%). Environmental monitoring did not prove the presence of KPC KP in the environment. During the observation of hand hygiene compliance frequent disinfection of gloves was observed and low compliance with hand hygiene after removing the gloves and low rate of compliance with hand hygiene after glove removal.
Conclusion: Factors associated with the spread of Klebsiella pneumoniae KPC included excessive number of hospitalized patients, lack of personal capacity, and an excessive unindicated use of gloves and their disinfection. The misuse of gloves during patient care activities increases the potential for cross-transmission of bacteria. In the future, we expect a change in the epidemiology of resistance, which relates to the selection pressure of antibiotics and disinfectants massively used during the COVID-19 pandemic.
Key words: outbreak, COVID-19, Klebsiella pneumoniae KPC, multidrug-resistant microorganisms, nosocomial infections.
Lek Obz, 2021, 70 (12): 481-484
Jaroslava BRŇOVÁ 1,2, Janka PRNOVÁ 1,2, Lenka REIZIGOVÁ 1,3, Martina HAVRIŠKO 1, Lukáš PAZDERKA 1,4, Denisa LOVECKÁ 5, Lucia ŠMIDOVIČOVÁ 5,6, Zuzana ŠKVARKOVÁ 2
1 Center of Microbiology and Infection Prevention at the Department of Laboratory Examination Methods in Health Care, Faculty of Health Care and Social Work, Trnava University in Trnava, Slovakia
2 Department of hospital hygiene and epidemiology, University Hospital Trnava, Slovakia
3 National Reference Center for the Prevention and Control of Nosocomial Infection, Regional Office of Public Health, Trenčín, Slovakia
4 Department of Clinical Microbiology, AnalytX s.r.o., Trnava, Slovakia
5 Faculty of Public Health, Slovak Medical University, Slovakia University Hospital Trnava, Slovakia
6 Department of Health Care, Trnava Self-Governing Region, Slovakia
Citácia:
BRŇOVÁ J., PRNOVÁ J., REIZIGOVÁ L. a kol.: Epidémia KPC Klebsiella pneumoniae počas druhej vlny pandémie COVID-19 v Univerzitej nemocnici Trnava. Lek Obz, 2021, 70 (12): 481-484
Cite:
BRŇOVÁ J., PRNOVÁ J., REIZIGOVÁ L. et al: Outbreak of KPC Klebsiella pneumoniae during second wave of COVID-19 pandemic in University hospital Trnava. Lek Obz, 2021, 70 (12): 481-484
