Abstract
INTRODUCTION. Stroke is one of the most common causes of mortality and long-term disability worldwide. In a sizeable amount of patients, a certain degree of neurological deficit persists after overcoming it. For this reason, it is necessary to develop therapeutic procedures that would help alleviate the consequences of this disease. Repetitive magnetic stimulation is a non-invasive neurostimulation and neuromodulation technique that uses the induction of a magnetic field to subsequently influence events in the brain in a complex manner. According to available scientific evidence, a supportive effect of repetitive magnetic stimulation can be expected to improve motor functions in patients after stroke.

OBJECTIVE. The presented article was created in the preparation of a research project in which we plan to evaluate the impact of repetitive transcranial magnetic stimulation on the recovery of motor functions in patients after stroke.

MATERIAL AND METHODS. In the first part of the article, we present a literature review of basic information related to the issue and the basis of the project. Detailed attention is paid to the mechanism of repetitive magnetic stimulation, the results of studies examining the effect of repetitive magnetic stimulation in animal models of stroke and the issue of safety of its application in the population of patients after stroke.

RESULTS. Research on animal models suggests that repetitive magnetic stimulation may be an effective method for influencing residual motor deficit. There is a growing body of scientific evidence in the medical literature of the safety of the methodology for use in a population of patients after stroke.

CONCLUSIONS. Repetitive transcranial magnetic stimulation appears to be a safe and effective method for improving motor functions in patients after stroke. Appropriate intervention timing and optimal parameters of applied repetitive transcranial magnetic stimulation must be revealed in future prospective studies (Ref. 41). Text in PDF www.lekarskyobzor.sk.

KEY WORDS: stroke, repetitive transcranial magnetic stimulation.
Lek obz 2022, 71 (9): 325-330

Katarína VALOVIČOVÁ 1, Pavel ŠIARNIK 1, Igor RIEČANSKÝ 2,3, Stanislava KLOBUCKÁ 4, Eva VASKÁ 5, Marek SÝKORA 1,6,
Peter TURČÁNI 1, Branislav KOLLÁR 1

1I. neurologická klinika Lekárskej fakulty Univerzity Komenského v Bratislave a Univerzitnej nemocnice Bratislava, prednosta
prof. MUDr. P. Turčáni, PhD.
2Centrum experimentálnej medicíny Slovenskej akadémie vied, Bratislava, riaditeľka doc. RNDr. O. Pecháňová, DrSc.
3Psychiatrická klinika Lekárskej fakulty Slovenskej zdravotníckej univerzity v Bratislave, prednostka doc. MUDr. Ľ. Forgáčová, PhD.
4Rehabilitačné centrum Harmony, n.o., Bratislava, primárka MUDr. S. Klobucká, PhD.
5Fakulta zdravotníckych vied, Univerzita sv. Cyrila a Metoda, Trnava, dekan prof. MUDr. Ľ. Gašpar, CSc.
6Neurological Intensive Care Unit and Stroke Unit, St. John of God Hospital, Viedeň, prednosta Prim. Univ.-Prof. dr. Wilfried Lang

CITE:
VALOVIČOVÁ K., ŠIARNIK P., RIEČANSKÝ I., KLOBUCKÁ S., VASKÁ E., SÝKORA M., TURČÁNI P., KOLLÁR B.: Therapeutic use of repetitive transcranial magnetic stimulation in pacients after stroke. Part I: Basic information and starting points of the project. Lek obz 2022, 71 (9): 325-330