Abstract

Background. Last decades in medicine are characterized with evaluation of new biomarkers, which may be helpful in the diagnosis, treatment and risk evaluation in the clinical practice.

Material and methods. To the known and already commonly used biomarkers in the last years also GDF-15 (growth differentiation factor 15) is included, which may have an additional role to such biomarkers as are troponins, or natriuretic peptides. GDF-15 protein can be easily determined in the circulation and therefore it represents an useful biomarker in the near future.

Conclusion. Increased levels may be useful in prediction of all cause mortality among these patients. This review presents its current potential role for the common clinical practice (tab. 1, lit. 56). Text in PDF www.lekarskyobzor.sk.  

KEY WORDS: biomarker, cardiovascular system, GDF-15.

Lek obz 2022, 71 (10): 370-375

Andrej DUKÁT 1, Ján KYSELOVIČ 1, Juraj PAYER 1, Marián BERNADIČ 2, Fedor ŠIMKO 2

1 V. interná klinika LF UK a UNB v Bratislave, prednosta prof. MUDr. J. Payer, PhD., MPH, FRCP
2 Ústav patologickej fyziológie LF UK v Bratislave, prednosta prof. MUDr. F. Šimko, PhD., FESC

Cite
DUKÁT A., KYSELOVIČ J., PAYER J., BERNADIČ M., ŠIMKO F.: Growth differentiation factor 15 – biomarker helpful in the diagnosis, treatment and risk evaluation in the clinical cardiology and medical practice. Lek obz 2022, 71 (10): 370-375