Abstract
Objective. Topiramate belongs to a group of anticonvulsants used to prevent epileptic seizures and migraine headaches. Increasing off-label indications lead to its increased medical use despite a wide spectrum of adverse events.

Case report. This case report demonstrates a 19-year-old female who complained of blurry vision 7 days after using topiramate for her migraine. On initial examination, acquired myopia was diagnosed and intraocular pressures were 23 mmHg and 28 mmHg in the right and left eyes, respectively. Further examinations confirmed the diagnosis of secondary closed-angle glaucoma.

Conclusion. Topiramate was immediately discontinued, appropriate treatment was administered, and after 4 days the patient had fully recovered (Fig. 2, Ref. 14). Text in PDF www.lekarskyobzor.sk.

KEY WORDS: topiramate, acute myopia, secondary closed-angle glaucoma, migraine, epilepsy.

Lek Obz 2022, 71 (10): 518-521

Michaela HÁJKOVÁ 1, Adriana TAKÁČOVÁ 1, Nora MAJTÁNOVÁ 1,2, Petr KOLÁŘ 1, 2

1 Očná klinika SZU a UN v Bratislave, prednosta prof. MUDr. P. Kolář, PhD.
2 Slovenská zdravotnícka univerzita, Bratislava, rektor Dr.h.c. prof. MUDr. P. Šimko, CSc.

CITE
HÁJKOVÁ M., TAKÁČOVÁ A., MAJTÁNOVÁ N. et al.: Topiramate-induced acute myopia and secondary closed-angle glaucoma. Lek Obz 2022, 71 (10): 518-521