Abstract
This study aims to explore new possibilities for the use of thymol in the context of colorectal cancer. Colorectal cancer still represents one of the most frequently occurring cancers in the world.
Linking this disease to the potential of naturally occurring substances such as thymol could help to make a significant shift in prevention and treatment. Our article mainly focuses on innovative and promising approaches such as encapsulation, nanoemulsions, targeted structural modifications of thymol, or personalized approach in the treatment of colorectal cancer. These are areas that have been the focus of intense research in recent years. This has resulted in the discovery of many therapeutic properties of thymol that are applicable to many cancers, including colorectal cancer. The limiting properties of thymol can be minimized or removed by targeted chemical modification. The use of encapsulation or nanoemulsions can increase the potency or stability of thymol and ensure a gradual release of the substance. The results have shown that personalized treatment of colorectal cancer, actively exploiting the knowledge gained, has its place (Ref. 49). Text in PDF www.lekarsky.herba.sk.
KEY WORDS: thymol, colorectal cancer, encapsulation, nanoemulsion, derivatives.
Lek Obz 2024, 73 (8): 268-272
Michaela BLAŽÍČKOVÁ, Katarína KOZICS
Department of Nanobiology, Cancer Research Institute SAS, Bratislava, Slovak Republic, vedúca pracoviska Mgr. A. Bábelová, PhD.