Abstract 
A group of patients with head and neck malignancies has a higher risk of developing duplex malignant tumors than the rest of the population. In the last decade, the incidence of duplex tumors has increased with a negative effect on patient survival. Most of these tumors are located in the oral cavity, pharynx, larynx, lungs, or esophagus.

The main reason for this topographic specificity is the exposure of the squamous epithelium of these organs to the same carcinogenic substances, especially tobacco and alcohol. In the presented work, we present the case reports of two patients with duplex carcinoma of the esophagus in the postoperative period after radical surgery of oral cavity carcinoma (Fig. 8, Ref. 13). Text in PDF www.lekarsky.herba.sk.
KEY WORDS: second primary tumour, follow up, squamous cell carcinoma. 
Lek Obz 2024, 73 (7): 257-260

Barbora HOCKOVÁ, Rastislav SLÁVIK, Juraj ABELOVSKÝ, Dušan PORUBAN, Adam STEBEL 
Klinika maxilofaciálnej chirurgie SZU, FNsP F.D. Roosevelta, Banská Bystrica, prednosta MUDr. MDDr. A. Stebel, PhD.